Day hotels available in Otay Mesa: 16Sort by:PopularityPorto Vista Hotel In Little ItalyPreviousNextPool access includedPorto Vista Hotel In Little ItalySee on mapLittle Italy4.2/5 | 40 ReviewsFree cancellationPayment at the hotelUS$89-51%US$180 per nightFree cancellationPayment at the hotelFromUS$89-51%US$180 per nightPrevious8am - 2pm10am - 5pm3pm - 11pmNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottPreviousNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottSee on mapCore-Columbia4.5/5 | 16 ReviewsFree cancellationPayment at the hotelUS$134-33%US$200 per nightFree cancellationPayment at the hotelFromUS$134-33%US$200 per nightPrevious8am - 2pm10am - 5pmNextManchester Grand Hyatt San DiegoPreviousNextPool access includedManchester Grand Hyatt San DiegoSee on mapMarina4.7/5 | 33 ReviewsFree cancellationPayment at the hotelUS$225-36%US$350 per nightFree cancellationPayment at the hotelFromUS$225-36%US$350 per nightPrevious9am - 5pm11am - 6pmNextMotel 6-San Diego, CA - DowntownPreviousNextMotel 6-San Diego, CA - DowntownSee on mapCoronado4.1/5 | 10 ReviewsFree cancellationPayment at the hotelUS$60-34%US$90 per nightFree cancellationPayment at the hotelFromUS$60-34%US$90 per nightPrevious8am - 2pm9am - 4pm1pm - 7pm5pm - 10pmNextDays Inn by Wyndham San Diego/Downtown/Convention CenterPreviousNextDays Inn by Wyndham San Diego/Downtown/Convention CenterSee on mapCore-Columbia4/5 | 32 ReviewsFree cancellationPayment at the hotelUS$80-58%US$189 per nightFree cancellationPayment at the hotelFromUS$80-58%US$189 per nightPrevious9am - 4pmNextThe Bristol Hotel San DiegoPreviousNextThe Bristol Hotel San DiegoSee on mapCore-Columbia4.7/5 | 7 ReviewsFree cancellationPayment at the hotelUS$104-26%US$139 per nightFree cancellationPayment at the hotelFromUS$104-26%US$139 per nightPrevious7am - 1pmNextResidence Inn by Marriott San Diego DowntownPreviousNextPool access includedResidence Inn by Marriott San Diego DowntownSee on mapLittle Italy4.6/5 | 14 ReviewsFree cancellationPayment at the hotelUS$150-35%US$229 per nightFree cancellationPayment at the hotelFromUS$150-35%US$229 per nightPrevious10am - 5pmNextBaymont by Wyndham San Diego DowntownPreviousNextBaymont by Wyndham San Diego DowntownSee on mapCore-Columbia4.4/5 | 12 ReviewsFree cancellationPayment at the hotelUS$75-56%US$169 per nightFree cancellationPayment at the hotelFromUS$75-56%US$169 per nightPrevious10am - 4pmNextHoliday Inn Express - Downtown San Diego, an IHG HotelPreviousNextPool access includedHoliday Inn Express - Downtown San Diego, an IHG HotelSee on mapCortez HillFree cancellationPayment at the hotelUS$124-39%US$203 per nightFree cancellationPayment at the hotelFromUS$124-39%US$203 per nightPrevious10am - 5pmNextCourtyard by Marriott San Diego DowntownPreviousNextCourtyard by Marriott San Diego DowntownSee on mapCore-Columbia4.8/5 | 13 ReviewsFree cancellationPayment at the hotelUS$179Free cancellationPayment at the hotelFromUS$179-17%US$215 per nightPrevious7am - 6pm9am - 4pm10am - 6pmNextHampton Inn San Diego-DowntownPreviousNextPool access includedHampton Inn San Diego-DowntownSee on mapSan Diego, CA4.6/5 | 5 ReviewsFree cancellationPayment at the hotelUS$145-52%US$299 per nightFree cancellationPayment at the hotelFromUS$145-52%US$299 per nightPrevious10am - 4pmNextMargaritaville Hotel San Diego Gaslamp QuarterPreviousNextPool access includedMargaritaville Hotel San Diego Gaslamp QuarterSee on mapEast Village4.9/5 | 22 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromUS$99-67%US$299 per nightSold out offersKimpton Hotel Palomar San DiegoPreviousNextPool access includedKimpton Hotel Palomar San DiegoSee on mapCore-Columbia4.8/5 | 7 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromUS$0Sold out offersThe El Cordova HotelPreviousNextPool access includedThe El Cordova HotelSee on mapCoronadoFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromUS$0Sold out offersThe Westin San Diego BayviewPreviousNextPool access includedThe Westin San Diego BayviewSee on mapCore-Columbia4.7/5 | 29 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromUS$0Sold out offersRamada by Wyndham San Diego National CityPreviousNextPool access includedRamada by Wyndham San Diego National CitySee on mapNational City4.1/5 | 12 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromUS$0Sold out offers1